Chemist - Clinical Biomarker Lead, Drug Development (m/f/d)

Beschreibung

(Senior) Clinical Biomarker Lead

Germany, Baden-Württemberg, Biberach

JOB ID: 2113813
JOB LEVEL: Experienced
FUNCTIONAL AREA: Research & Development
SCHEDULE: Full-Time

OUR COMPANY

At Boehringer Ingelheim we develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company, we focus on long-term performance. We believe that, if we have talented and ambitious people who are passionate about innovation, there is no limit to what we can achieve; after all, we started with just 28 people. Now, we are powered by 50,000 employees globally who nurture a diverse, collaborative and inclusive culture.

THE POSITION

Are you an expert in Translational Medicine and Biomarkers? Do you have experience in drug development and a deep knowledge and practical experience in the analysis of biomarkers with a focus on mass spectrometry?

We are offering an exciting opportunity to join the global department Translational Medicine & Clinical Pharmacology (TMCP) at our site in Biberach, Germany. TMCP is accountable for bringing clinical drug candidates across all therapeutic areas to the early clinical development milestone Proof-of-Clinical-Principle by applying state-of-the-art biomarker and translational approaches.

As Clinical Biomarker Lead Mass Spectrometry, you support drug development projects in the transition from research to clinical development and up to clinical phase III, including submission, by providing your expertise for liquid chromatography–mass spectrometry (LC–MS) based analysis of biomarkers such as proteins, peptides, lipids and endogenous small molecules.

Are you looking for a new professional challenge? If so, seize the opportunity and apply as (Senior) Clinical Biomarker Lead Mass Spectrometry.

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Tasks & responsibilities

• By using appropriate concepts and relevant methodology, you ensure the successful operational implementation of biomarker strategies in clinical trials and translational studies of various therapeutic areas.
• You collaborate with contract research organizations on all aspects of biomarker analytics, including method development, method transfer, fit-for-purpose validation and oversight of clinical study measurements.
• As an expert, you evaluate and report the results of clinical biomarker assays.
• In close collaboration with other early clinical development functions, you ensure that the biomarker data package enables Proof-of-Clinical-Principle and supports the Target Product Profile.
• With your analytical expertise, you support experimental medicine studies and/or projects in collaboration with internal and external partners. You act as connector and establish a network of academic and industrial partners to ensure a continuous exchange about biomarker methodology and endpoints across projects.
• With your deep knowledge, you act as a consultant for clinical applications of LC-MS/MS and high-resolution MS based analyses.

Requirements

• PhD (in Analytical Chemistry, Pharmacy, Biochemistry, or related subjects) with a strong record of accomplishment of independent clinical/research activities with working experience in a pharmaceutical or diagnostic company or as an independent academic researcher
• Expert knowledge and hands-on experience in LC-MS as well as in quantitation of small molecules and peptide/protein/lipid biomarkers in samples from various biological matrices by means of LC-MS including corresponding sample preparation techniques, ideally in the setting of clinical trials
• Credible knowledge of and experience with biomarkers in clinical drug development with an understanding of clinical biomarker applications, evaluation and analysis of biomarker data and their linkage to pathophysiology and clinical endpoints
• Additional experience in advanced immunoassay-based biomarker analysis and in statistical analysis of data would be a plus (e.g. multivariate analysis, analysis of large data sets)
• Excellent leadership skills, successfully proven in project team and line management settings, and proven ability to deliver results
• Innovative mindset to evaluate cutting-edge technology and analytical platforms and ability to project opinions and knowledge with confidence, authority, respect, and diplomacy when interacting with all levels of internal and external partners
• The international nature of the task requires excellent English - both spoken and written

EFFECTS OF COVID-19We will continue to hire talented people and we look forward to receiving your applications. As a result of COVID-19, we have introduced alternative working arrangements to ensure that our employees can stay safe and healthy, because the health of our employees is among our top priorities. At all company locations, we work remotely whenever possible. Additionally, we are now hosting virtual video interviews for applicants. During the limited in-person interviews we still have during this time, we pay special attention to distance and the hygiene rules recommended by the Robert Koch Institute. New employees who do not start on site in production or the laboratories are sent the necessary IT equipment, our Welcome Days take place online, and we plan to conduct their onboarding training virtually whenever possible.

WHY BOEHRINGER INGELHEIM?

This is where you can grow, collaborate, innovate and improve lives.

We offer challenging work in a respectful and friendly global working environment surrounded by a world of innovation driven mindsets and practices. In addition, learning and development for all employees is key, because your growth is our growth. We also offer a competitive salary, generous amount of vacation time, and numerous benefits towards your wellness & financial health and work-life balance. Plus, an in-house doctor and best-in-class cafeterias and coffee bars to keep you energized and healthy. To learn more about what benefits could be waiting for you, please visit our Career area.

Want to learn more about us? Visit https://www.boehringer-ingelheim.com/

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or national origin.